Nephropathies [529 genes]

Health in Code offers a genetic diagnostic service aimed at diseases affecting the kidneys. There are more than 500 genes associated with inherited kidney diseases, which represent more than 5% of all known genetic diseases. It is estimated that about 10% of kidney diseases that require transplantation in adults, and practically all in children, are hereditary, and most of them are monogenic in nature. The prevalence of these diseases is highly variable, since they include both diseases with high impact in the general population, such as polycystic kidney disease (prevalence 1-9/10,000), and rare, low-incidence syndromes that in many cases have unknown prevalence. Due to the heterogeneity of these diseases and the nature of the genetic defects, a correct diagnosis can lead to the identification of the cause of the disease and prediction of disease progression in cases where it is possible.
We take an integral approach to genetic kidney diseases, with a portfolio of over 30 panels that cover 529 genes associated with the development of kidney diseases.