• Pharmacogenetics global panel [30 genes]    (all clinical areas included)

    Ref.: S-202212590|Turnaround time (TAT) 25 days

  • Pharmacogenetics service for a clinical area (single clinical area)

    Ref.: S-202212575|Turnaround time (TAT) 25 days

    • Central nervous system
    • Digestive system and metabolism
    • Analgesics, anesthetics and musculoskeletal system
    • Cardiovascular system
    • Immunosuppressive agents
    • Respiratory system
    • Antineoplastic agents
    • Anti-infective agents
    • Genitourinary system and sex hormones
    • Dermatology
    • Antidotes
  • Clozapine Pharmacogenetics [10 genes]

    Ref.: S-202110203|Turnaround time (TAT) 10 days

  • Pharmacogenetics of lipid-lowering agents [6 genes]

    Ref.: S-201907369|Turnaround time (TAT) 25 days

  • Antiplatelet and anticoagulation pharmacogenetics [13 genes]

    Ref.: S-202008274|Turnaround time (TAT) 25 days

  • Dihydropyrimidine dehydrogenase deficiency (5-fluorouracil toxicity). Sequencing of DPYD gene
    [1 gene]

    Ref.: S-202212057|Turnaround time (TAT) 25 days

Genotyping services

  • Pharmacogenetics DPYD genotyping 4 variants

    Ref.: S-202110029|Turnaround time (TAT) 5 days

  • Pharmacogenetics CYP2C9 genotyping 2 variants

    Ref.: S-202110395|Turnaround time (TAT) 10 days

  • Pharmacogenetics CYP2C19 genotyping by qPCR 4 variants

    Ref.: S-202313820|Turnaround time (TAT) 10 days

  • Pharmacogenetics TYMS genotyping 1 variant

    Ref.: S-202110298|Turnaround time (TAT) 10 days

  • Pharmacogenetics UGT1A1 genotyping (Sanger)

    Ref.: S-202210996|Turnaround time (TAT) 10 days

  • Pharmacogenetics UGT1A1 genotyping (Expansions)

    Ref.: S-202212834|Turnaround time (TAT) 10 days

Other services

TAT (turnaround time): 35 days

Individual gene sequencing and interpretation service. Depending on its size and on the regions of interest, we can offer an approach based on Sanger sequencing or on NGS (enrichment using amplicons or hybridization probes). The NGS-based approach allows detecting copy number variations (CNVs).

TAT (turnaround time): 35 days

Semiquantitative technique that is widely applied in molecular genetic laboratories and that allows diagnosing pathologies caused by copy number variations and, in some cases, by alterations in DNA methylation. A wide variety of commercial kits are available to test individual genes, gene panels related to specific pathologies, or large chromosomal regions involved in microdeletion/microduplication syndromes. HIC offers MLPA services based on MRC-Holland kits.